Molecular Cancer - Latest Comments

Typographical errors

Rossella Rota — 2012-01-05T11:55:36Z

In the "miRNAs as diagnostic and prognostic tools in RMS" Section, third paragraph, the sentence: "...these authors identified an inverse correlation between the
expression of miR-206 and overall survival...." has to be read: "...these authors identified an inverse correlation between the
expression of miR-206 and POOR overall survival...". Moreover, in the fifth paragraph the sentence: "Considering that miR-206 levels are inversely correlated with good prognosis,..." has to be read: "Considering that miR-206 levels are inversely correlated with POOR prognosis,..."

corrections in tables

Francois Bertucci — 2011-11-04T15:17:17Z

We apologise for two hazard ratio inversions that do not change the signification of the results and the conclusions of our work.
In table 4, immune metagene row, first multivariate analysis, readers should read "0.47 [0.29-0.76]".
In table 5, immune metagene row, readers should read "0.45 [0.29-0.69]".

Correction of the legend of additional file 1

Xingming Deng — 2011-10-25T16:22:17Z

The sentence ¿"in the absence or presence of PD98059 (10 uM)" was originally included in the additional file 1 legend (B) as a typing error, and the various cell types were only treated with GCDA. Therefore, the sentence "in the absence or presence of PD98059 (10 uM)" should be removed from the legend (B) of ¿Additional file 1¿. This change in the legend more accurately describes the data in Figure S1 and has no effect on the experiment, the interpretation or the conclusions drawn.

Corrigendum

Frances Wadelin — 2010-09-14T09:24:24Z

The authors would like to correct an editing error in the statement at the end of paragraph 2 in the section titled: cellular functions of PRAME: repression of retinoic acid receptor signalling. In fact, reference 47 reported that the interaction of PRAME with RARa was ligand-dependent.

Mismatch repair deficiencies transforming stem cells into cancer stem cells and therapeutic implications

Minal Garg — 2007-05-20T01:30:13Z

Thanks for the interest. Although cancer stem cells gain self renewal capacity but they accumulate many harmful mutations and lose the property of differentiation as embryonic stem cells have and therefore, they can not replace embryonic stem cells for the treatment of damaged cells.

question

brian jennings — 2007-05-01T16:21:14Z

I am a senior in High School taking an AP Bio course, and we just learned a little about cancer cells. If they are so similar to stem cells in that they are pluripotent then would it be possible that they could be used for stem cell research and possibly treatment for damaged cells, like the research that is being done with embryonic stem cells?

thanks