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Research   Open Access

Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration

Liangping Yuan, Hongying Zhang, Jingbo Liu, Joshua B Rubin, Yoon-Jae Cho, Hui Kuo Shu, Matthew Schniederjan, Tobey J MacDonald Molecular Cancer 2013, 12:18 (5 March 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Effects of HDM2 antagonism on sunitinib resistance, p53 activation, SDF-1 induction, and tumor infiltration by CD11b+/Gr-1+ myeloid derived suppressor cells

David J Panka, Qingjun Liu, Andrew K Geissler, James W Mier Molecular Cancer 2013, 12:17 (5 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer

Rebekah L Zinn, Eric E Gardner, Irina Dobromilskaya, Sara Murphy, Luigi Marchionni, Christine L Hann, Charles M Rudin Molecular Cancer 2013, 12:16 (2 March 2013)

Abstract | Full text | PDF | PubMed

Reviewer acknowledgement   Open Access

Thanking our peer reviewers

Alan Storey Molecular Cancer 2013, 12:10 (1 March 2013)

Abstract | Full text | PDF

Research   Open Access

MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2

Mitsuhiro Matsuo, Chisato Nakada, Yoshiyuki Tsukamoto, Tsuyoshi Noguchi, Tomohisa Uchida, Naoki Hijiya, Keiko Matsuura, Masatsugu Moriyama Molecular Cancer 2013, 12:15 (25 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Serotonin promotes the proliferation of serum-deprived hepatocellular carcinoma cells via upregulation of FOXO3a

Chao Liang, Wei Chen, Xiao Zhi, Tao Ma, Xuefeng Xia, Hao Liu, Qi Zhang, Qida Hu, Yun Zhang, Xueli Bai, Tingbo Liang Molecular Cancer 2013, 12:14 (19 February 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer

Robert S Hudson, Ming Yi, Natalia Volfovsky, Robyn L Prueitt, Dominic Esposito, Stefano Volinia, Chang-Gong Liu, Aaron J Schetter, Katrien Van Roosbroeck, Robert M Stephens, George A Calin, Carlo M Croce, Stefan Ambs Molecular Cancer 2013, 12:13 (14 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research   Open Access

Head and neck cancer cells and xenografts are very sensitive to palytoxin: decrease of c-jun n-terminale kinase-3 expression enhances palytoxin toxicity

Tibor Görögh, László Bèress, Elgar S Quabius, Petra Ambrosch, Markus Hoffmann Molecular Cancer 2013, 12:12 (14 February 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer cell type

Steven Rust, Sandrine Guillard, Kris Sachsenmeier, Carl Hay, Max Davidson, Anders Karlsson, Roger Karlsson, Erin Brand, David Lowne, John Elvin, Matt Flynn, Gene Kurosawa, Robert Hollingsworth, Lutz Jermutus, Ralph Minter Molecular Cancer 2013, 12:11 (13 February 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer

Yuanyuan Li, Syed M Meeran, Shweta N Patel, Huaping Chen, Tabitha M Hardy, Trygve O Tollefsbol Molecular Cancer 2013, 12:9 (4 February 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Quantitation of cell-free DNA and RNA in plasma during tumor progression in rats

Dolores C García-Olmo, María G Picazo, Inmaculada Toboso, Ana I Asensio, Damián García-Olmo Molecular Cancer 2013, 12:8 (4 February 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site

Kurtis Eisermann, Carly J Broderick, Anton Bazarov, Mustafa M Moazam, Gail C Fraizer Molecular Cancer 2013, 12:7 (1 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

Short communication   Open Access

POU1F1 is a novel fusion partner of NUP98 in acute myeloid leukemia with t(3;11)(p11;p15)

Susana Lisboa, Nuno Cerveira, Susana Bizarro, Cecília Correia, Joana Vieira, Lurdes Torres, José M Mariz, Manuel R Teixeira Molecular Cancer 2013, 12:5 (18 January 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells

Charlotte M Smith, Volker Haucke, Adam McCluskey, Phillip J Robinson, Megan Chircop Molecular Cancer 2013, 12:4 (17 January 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

The Wilms’ tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells

Adina Brett, Sony Pandey, Gail Fraizer Molecular Cancer 2013, 12:3 (8 January 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Decreased expression of ADAMTS-1 in human breast tumors stimulates migration and invasion

Vanessa M Freitas, Jônatas Bussador do Amaral, Thaiomara A Silva, Emerson S Santos, Flávia R Mangone, João de Jesus Pinheiro, Ruy G Jaeger, Maria A Nagai, Gláucia Maria Machado-Santelli Molecular Cancer 2013, 12:2 (5 January 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

Neel Sengupta, Christopher Yau, Anuratha Sakthianandeswaren, Dmitri Mouradov, Peter Gibbs, Nirosha Suraweera, Jean-Baptiste Cazier, Guadalupe Polanco-Echeverry, Anil Ghosh, Mohamed Thaha, Shafi Ahmed, Roger Feakins, David Propper, Sina Dorudi, Oliver Sieber, Andrew Silver, Cecilia Lai Molecular Cancer 2013, 12:1 (3 January 2013)

Abstract | Full text | PDF | PubMed

Research   Open Access

Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines

Andrea Cavazzoni, Roberta R Alfieri, Daniele Cretella, Francesca Saccani, Luca Ampollini, Maricla Galetti, Federico Quaini, Gallia Graiani, Denise Madeddu, Paola Mozzoni, Elena Galvani, Silvia La Monica, Mara Bonelli, Claudia Fumarola, Antonio Mutti, Paolo Carbognani, Marcello Tiseo, Elisabetta Barocelli, Pier Giorgio Petronini, Andrea Ardizzoni Molecular Cancer 2012, 11:91 (12 December 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Deficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mouse

Shioko Kimura, Jorge Paiz, Mitsuhiro Yoneda, Taketomo Kido, Charles Vinson, Jerrold M Ward Molecular Cancer 2012, 11:90 (12 December 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Highly efficient site-specific transgenesis in cancer cell lines

Iacovos P Michael, Claudio Monetti, Anthony C Chiu, Puzheng Zhang, Takeshi Baba, Koichiro Nishino, Siamak Agha-Mohammadi, Knut Woltjen, Hoon-Ki Sung, Andras Nagy Molecular Cancer 2012, 11:89 (11 December 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

Toru Furukawa, Etsuko Tanji, Yuko Kuboki, Takashi Hatori, Masakazu Yamamoto, Kyoko Shimizu, Noriyuki Shibata, Keiko Shiratori Molecular Cancer 2012, 11:88 (10 December 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation

Yijing Li, Lei Wang, Loretta Pappan, Amy Galliher-Beckley, Jishu Shi Molecular Cancer 2012, 11:87 (23 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Gene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin-like growth factor 2 imprinting system

Zhen-Lin Nie, Yu-Qin Pan, Bang-Shun He, Ling Gu, Li-Ping Chen, Rui Li, Ye-Qiong Xu, Tian-Yi Gao, Guo-Qi Song, Andrew R Hoffman, Shu-Kui Wang, Ji-Fan Hu Molecular Cancer 2012, 11:86 (21 November 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells

Nicole Grabinski, Florian Ewald, Bianca T Hofmann, Katharina Staufer, Udo Schumacher, Björn Nashan, Manfred Jücker Molecular Cancer 2012, 11:85 (20 November 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosis

Nadzeya Goncharenko-Khaider, Isabelle Matte, Denis Lane, Claudine Rancourt, Alain Piché Molecular Cancer 2012, 11:84 (17 November 2012)

Abstract | Full text | PDF | PubMed

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