Methylation of XPG promoter in human tumors. Panel A. Analysis of human XPG promoter and identification of putative CpG islands from which primers for methylation specific PCR were designed. Panel B. XPG Methylation specific PCR in tumor and blood samples from patients with ovarian cancer. Samples in which methylated DNA was detectable have been highlighted. Panel C. XPA Methylation specific PCR in the same tumor samples used for XPG methylation analysis.
Sabatino et al. Molecular Cancer 2010 9:259 doi:10.1186/1476-4598-9-259