Elevation of AGR2. A. Fold-changes of AGR2 in pancreatic juice from patients with PanIN3 detected by quantitative proteomics analysis in comparison to controls. B. Detection of AGR2 by IHC in neoplastic pancreas ducts. Strong staining of AGR2 was detection in the neoplastic ducts of PanIN cases a and c (I and II), as well as the neoplastic region of pancreatic cancer (VI). AGR2 was not detected in the normal pancreas duct (III).
Chen et al. Molecular Cancer 2010 9:149 doi:10.1186/1476-4598-9-149