Figure 8.

EBNA1 inhibits the phosphorylation of IκBα and IKKα/β in carcinoma cells. (A) Western blot analysis of total and phosphorylated IκBα (ser32) in Ad/AH and Hone1 cells stably expressing EBNA1 or a neomycin control vector (neo).(B) Western blot analysis of total IKKα, IKKβ, IKKγ and phosphorylated IKKα/β (IKKα Ser176/180 and IKKβ Ser177/181) in Ad/AH and Hone1 cells stably expressing EBNA1 or a neomycin control vector (neo). Western blotting for EBNA1 and β-actin serve as EBNA1 expression and protein loading controls, respectively.