EM011 treatment induces DNA fragmentation and apoptosis. A shows DAPI-stained micrographs for control (left) and 72 hrs drug exposed (right) A549 cells using a 63× objective. B. Quantitation of percent TUNEL-positive cells for EM011-treated cells for 0, 48 and 72 hrs. Values, mean of three independent experiments; bars, SD; (*, p < 0.05).
Karna et al. Molecular Cancer 2009 8:93 doi:10.1186/1476-4598-8-93