EM011 suppresses proliferation of human lung cancer cells. A. A panel of lung cancer cells ((H322 M, H266, H266B, H23, H460, HOP-92, HOP-62, H1299, A549, H522, H157, and H1792) were treated with gradient concentrations of EM011 for 72 hrs and the IC50 values were evaluated by the sulforhodamine B (SRB) in vitro cell proliferation assay. The values and error bars shown in the graph represent average and standard deviations, respectively, of three independent experiments (p < 0.05). B. Phase-contrast images (10×) of A549 cells treated with 25 μM EM011 for 0, 24, 48 and 72 hrs.
Karna et al. Molecular Cancer 2009 8:93 doi:10.1186/1476-4598-8-93