Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers

doi:10.1186/1476-4598-8-43

Molecular Cancer

Volume 8

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Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers

Chun Hei Antonio Cheung¹ , Huang-Hui Chen¹ , Ching-Chuan Kuo¹ , Chi-Yen Chang¹ , Mohane S Coumar² , Hsing-Pang Hsieh² and Jang-Yang Chang¹^,3

¹National Institute of Cancer Research, National Health Research Institutes, Tainan 704, Taiwan R.O.C

²Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan, Miaoli County 350, Taiwan R.O.C

³Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan 704, Taiwan R.O.C

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Molecular Cancer 2009, 8:43doi:10.1186/1476-4598-8-43


Published:	3 July 2009

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Additional file 1:

Analysis of the cell cycle distribution. (A) KB cells were treated with various concentrations of BPR0L075 for 24 h. Cells were stained with propidium iodide and subsequent analyzed by flow cytometry. (B) KB and KB-L30 cells cultured under BPR0L075-free conditions were stained with propidium iodide and subsequent analyzed by flow cytometry.

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