Figure 4.

Correlation between BLI and direct tumor volume determination in subcutaneous tumors. MC38Luc1 cells (10⁶) were injected subcutaneously in the right hind flank of C57BL/6 mice (n = 14), and tumor progression was evaluated weekly by either BLI or direct measurement. A – Monitorization of tumor volume by direct measurement (calliper, black circles) corresponds to the left Y axis. Light emission quantified by BLI is represented as a dotted line and the scale corresponds to photons/s × 10³ in the right Y axis. Error bars represent standard deviations. C-D – Correlation between light emission and direct tumor measurement 2 weeks (C) or 4 weeks (D) after cell implantation (log₁₀ conversion of values).