Table 1

Sequence identity and similarity shown by human and non-human TIMPs compared to the human TIMP-4.

Protein
Identity
(%)
Similarity
(%)

hTIMP-1
37
57
hTIMP-2
51
70
hTIMP-3
51
70
paTIMP-4
100
-
muTIMP-4
91
95
raTIMP-4
92
96
boTIMP-4
90
96
tkTIMP-4
55
73
drTIMP*
21
43

The amino acid sequences analyzed are the same as shown in Fig. 1 and the analysis was performed with BioEdit (Hall, T.A., 1999. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT.Nucl. Acids. Symp. Ser. 41:95–98).

* Drosophila melanogaster TIMP (gi 4157982)

Melendez-Zajgla et al. Molecular Cancer 2008 7:85   doi:10.1186/1476-4598-7-85