Research
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells
1 Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, M5T 3L9, Canada
2 Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, M5G 1X5, Canada
3 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada
Molecular Cancer 2008, 7:73 doi:10.1186/1476-4598-7-73
Published: 30 September 2008Additional files
Additional file 1:
Supplementary Information. This contains the Supplementary Methods information and the Supplementary figure legends.
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Additional file 2:
Supplementary figure 1. Active Rac1 binds to the concensus TBE in vitro as shown by electrophoretic mobility shift assay (EMSA).
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Additional file 3:
Supplementary figure 2. Active Rac1 enhances transcription from Wnt-responsive promoters.
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Additional file 4:
Supplementary figure 3. Wnt3a-CM stimulates the canonical Wnt pathway in 293T cells.
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