Figure 4.

Spectral karyotyping and array comparative genomic hybridization analyses of transformed MCF-10A cells derived from large tumors grown in nude mice. A. SKY analysis of control MCF-10A and transformed MCF10AαL cells. *sign shows chromosomal alterations between control and transformed cells. B. Array CGH of MCf10AαL cells hybridized against control MCF-10A cells shows chromosomal alterations (indicated by arrows) correlated with those identified by SKY.