Figure 4.

Effect of different mutations of β-catenin on the expression of a reporter gene with the main 5'-enhancer of GS. Cells from the cell-line HuH7 were transfected with the reporter gene 'HIII/EV_pT81' containing the main GS 5'-enhancer together with different expression plasmids for β-catenin forms (compare legend to Fig. 3). Expression was compared to expression from pT81 in order to determine the factor of enhancement mediated by the mutants.