Figure 6.

Survival of WSU-FSCCL-bearing SCID mice according to ApoG2 treatment and H & E stains of bone marrow sections. WSU-FSCCL cells were injected into the intraperitoneal cavity at 5 × 10⁶ cells. 25 mg/kg QD × 5 of ApoG2 was injected intravenously or intraperitoneally on day 7 post inoculation. Statistical comparison of survival curves for i.v. treatment and untreated control show a chi square of 8.005 and P = 0.0047. Statistical comparison of survival curves for i.p. treatment and untreated control show a chi square of 4.397 and P = 0.0360 (A). Replacement of the bone marrow with WSU-FSCCL cells in the control mouse (B). Negative bone marrow of intravenous (C) and intraperitoneal (D) treatment with ApoG2.