Figure 4.

Effects of curcumin and/TRAIL on cell cycle inhibitors and cyclin D1. (A), Immunohistochemistry was performed to measure the expression of cell cycle inhibitors (p21^/WAF1 and p27^/KIP1) and cyclin D1 in tumor tissues derived from control and/or treated mice on week 6. (B), Expression of p21^/WAF1, p27^/KIP1, cyclin D1 and β-actin in tumor tissues derived on week 6 were measured by the Western blot analysis.