Figure 6.

Immunofluorescence image shows greater uptake of BODIPY FL hyaluronic acid by MMs with higher Fra-1 expression levels (SV40-) (A). Internalization of the BODIPY FL HA probe (green) was visualized by fluorescence confocal microscopy. This internalization is reduced in the SV40+ line with low basal Fra-1 (red) expression (B) or those with high basal Fra-1 expression after Fra-1 knock-down (right panel).