Table 2

Predictors of microsatellite status identified by Support Vector Machine and PAM algorithms.

Probe
Symbol

Average expression
p-value
SVM* strength
PAM* score


Gene name
MSS
MSI-H


MSI-H
MSS

hsa-mir-223-prec
miR-223

0.97
1.84
4.69E-02
-
0.4929
-0.3429
hsa-mir-155-prec
miR-155 (BIC)

0.97
1.29
2.34E-02
-
0.4439
-0.3088
AL137343
FAM84A
family with sequence similarity 84, member A
1.51
0.45
1.07E-02
-
-0.0208
0.0145
NM_004183
VMD2
vitelliform macular dystrophy 2
2.09
0.38
8.73E-03
-
-0.1832
0.1274
NM_006113
VAV3
vav 3 oncogene
1.62
0.47
5.98E-03
13.96
-0.0533
0.0371
NM_005953
MT2A
metallothionein 2A
0.57
1.92
5.93E-03
16.34
0.8995
-0.6258
AK026372
KIAA1718

1.27
0.72
5.09E-03
16.02
-
-
hsa-mir-191-prec
miR-191

1.28
1.00
4.74E-03
-
0.0377
-0.0263
NM_017726
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
1.31
0.52
3.88E-03
14.58
-
-
NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
1.49
0.76
3.37E-03
16.49
-
-
AF273051
CCDC68
coiled-coil domain containing 68
2.21
0.84
2.49E-03
15.87
-0.0541
0.0376
NM_016328
GTF2IRD1
GTF2I repeat domain containing 1
1.49
0.87
2.13E-03
13.13
-
-
NM_001657
AREG
amphiregulin
2.10
0.69
1.04E-03
-
-0.0725
0.0504
AB033045
KIAA1219
hypothetical protein LOC57148
1.33
0.83
8.11E-04
15.87
-
-
hsa-mir-032-precNo2
miR-032

1.17
0.91
6.48E-04
14.02
0.0732
-0.0509
NM_004485
GNG4
guanine nucleotide binding protein (G protein), gamma 4
1.46
0.81
6.47E-04
16.49
-
-
NM_018267
H2AFJ
H2A histone family, member J
1.43
0.92
6.47E-04
13.96
-
-
AK000276
NKD1
naked cuticle homolog 1
2.47
0.77
4.55E-04
17.48
-0.1542
0.1072
NM_003878
GGH
gamma-glutamyl hydrolase
2.10
0.61
7.97E-05
15.87
-0.2232
0.1553
AK025215
C13ORF18
chromosome 13 open reading frame 18
2.41
0.66
4.40E-05
16.49
-0.3093
0.2152
NM_017763
RNF43
ring finger protein 43
2.10
0.57
2.91E-05
17.48
-0.2886
0.2008
NM_004693
K6HF
cytokeratin type II
1.24
0.80
2.91E-05
14.6
-
-
NM_002657
PLAGL2
pleiomorphic adenoma gene-like 2
1.37
0.76
2.91E-05
19.32
-
-
hsa-mir-025-prec
miR-025

1.52
0.84
2.14E-05
17.48
-
-
hsa-mir-092-prec-13=092-1No2
miR-092-1

1.50
0.65
1.87E-05
17.48
-
-
hsa-mir-092-prec-X=092-2
miR-092-2

1.60
0.64
1.87E-05
14.43
-
-
hsa-mir-093-prec-7.1=093-1
miR-093-1

1.23
0.9
1.87E-05
-
0.0084
-0.0058

* SVM: Support Vector Machine; PAM: Prediction Analysis of Microarray

Lanza et al. Molecular Cancer 2007 6:54   doi:10.1186/1476-4598-6-54