|
Gene Transcripts significantly down-regulated in BCC compared to normal skin specimens (≥1.2 fold; ≥100; p < 0.05). |
|||||
| probe set |
gene |
Accession |
fold change |
Difference |
P value |
|
|
|||||
| 239929_at |
hypothetical protein FLJ32569 |
AA918425 |
-28.24 |
-3433.29 |
0.014118 |
| 208962_s_at |
fatty acid desaturase 1 |
BE540552 |
-20.2 |
-3188.7 |
0.045399 |
| 229476_s_at |
thyroid hormone responsive (SPOT14 homolog, rat) |
AW272342 |
-17.15 |
-4660.08 |
0.034919 |
| 207275_s_at |
acyl-CoA synthetase long-chain family member 1 |
NM_001995 |
-15.11 |
-1865.7 |
0.039975 |
| 206799_at |
secretoglobin, family 1D, member 2 |
NM_006551 |
-14.97 |
-1291.31 |
0.042413 |
| 234513_at |
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like |
AF292387 |
-13.28 |
-670.81 |
0.022544 |
| 221561_at |
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 |
L21934 |
-12.23 |
-998.57 |
0.008422 |
| 206714_at |
arachidonate 15-lipoxygenase, second type |
NM_001141 |
-11.45 |
-3891.76 |
0.045644 |
| 214240_at |
galanin |
AL556409 |
-11.12 |
-1590.25 |
0.015802 |
| 244661_at |
gb:AA946876/DB_XREF=gi:3110271/DB_XREF=oq53c11.s1/CLONE= |
AA946876 |
-10.56 |
-399.74 |
0.017168 |
| 244780_at |
sphingosine-1-phosphate phosphotase 2 |
AI800110 |
-9.79 |
-351.6 |
0.024348 |
| 201625_s_at |
insulin induced gene 1 |
BE300521 |
-9.72 |
-1591.34 |
0.030044 |
| 231810_at |
BRI3 binding protein |
BG106919 |
-8.9 |
-877.2 |
0.021503 |
| 1565162_s_at |
microsomal glutathione S-transferase 1 |
D16947 |
-8.6 |
-1071.37 |
0.030259 |
| 238121_at |
Transcribed locus, weakly similar to XP_341569.1 similar to ORF4 |
AI473796 |
-8.29 |
-445.99 |
0.042733 |
| 211056_s_at |
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta |
BC006373 |
-7.88 |
-1432.56 |
0.032165 |
| 229957_at |
Branched chain keto acid dehydrogenase E1, alpha polypeptide |
BF446281 |
-7.63 |
-1214.3 |
0.025272 |
| 204675_at |
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta |
NM_001047 |
-7.35 |
-2832.7 |
0.027894 |
| 233030_at |
adiponutrin |
AK025665 |
-7.35 |
-1220.35 |
0.031698 |
| 231736_x_at |
microsomal glutathione S-transferase 1 |
NM_020300 |
-7.28 |
-2497.22 |
0.031804 |
| 205029_s_at |
fatty acid binding protein 7, brain |
NM_001446 |
-7.24 |
-524.52 |
0.021739 |
| 201627_s_at |
insulin induced gene 1 |
NM_005542 |
-7.23 |
-627.89 |
0.049971 |
| 209522_s_at |
carnitine acetyltransferase |
BC000723 |
-7.23 |
-2039.08 |
0.020824 |
| 226064_s_at |
diacylglycerol O-acyltransferase homolog 2 (mouse) |
AW469523 |
-7.1 |
-2291.54 |
0.032748 |
| 231156_at |
gb:AW242782/DB_XREF=gi:6576459/DB_XREF=xm89g06.x1/CLONE |
AW242782 |
-7.09 |
-339.26 |
0.045195 |
| 223184_s_at |
1-acylglycerol-3-phosphate O-acyltransferase 3 |
BC004219 |
-7.01 |
-1374.94 |
0.045149 |
| 232428_at |
monoacylglycerol O-acyltransferase 2 |
AK000245 |
-6.97 |
-182.68 |
0.038707 |
| 1558846_at |
Pancreatic lipase-related protein 3 |
AL833418 |
-6.71 |
-2007.72 |
0.044402 |
| 205030_at |
fatty acid binding protein 7, brain |
NM_001446 |
-6.41 |
-1864.48 |
0.021392 |
| 205843_x_at |
carnitine acetyltransferase |
NM_000755 |
-6.41 |
-1166.98 |
0.020573 |
| 224435_at |
chromosome 10 open reading frame 58///chromosome 10 open reading |
BC005871 |
-6.37 |
-1905.14 |
0.007356 |
| 1560507_at |
Diacylglycerol O-acyltransferase 2-like 3 |
BC039181 |
-6.28 |
-441.54 |
0.028259 |
| 215726_s_at |
cytochrome b-5 |
M22976 |
-5.95 |
-3458.82 |
0.02416 |
| 220431_at |
DESC1 protein |
NM_014058 |
-5.94 |
-112.38 |
0.029175 |
| 225716_at |
gb:AI357639/DB_XREF=gi:4109260/DB_XREF=qy15b05.x1/CLONE= |
AI357639 |
-5.94 |
-1718.34 |
0.01598 |
| 204388_s_at |
monoamine oxidase A |
NM_000240 |
-5.89 |
-362.75 |
0.037779 |
| 45288_at |
abhydrolase domain containing 6 |
AA209239 |
-5.83 |
-698.25 |
0.020361 |
| 218804_at |
transmembrane protein 16A |
NM_018043 |
-5.75 |
-234.79 |
0.045057 |
| 228479_at |
gb:AI094180/DB_XREF=gi:3433156/DB_XREF=qa29b09.s1/CLONE= |
AI094180 |
-5.7 |
-1191.04 |
0.029615 |
| 227804_at |
hypothetical protein BC014072 |
BE328850 |
-5.62 |
-363.64 |
0.043913 |
| 234312_s_at |
acetyl-Coenzyme A synthetase 2 (ADP forming) |
AK000162 |
-5.54 |
-1297.68 |
0.044265 |
| 1562528_at |
RAR-related orphan receptor A |
BC040965 |
-5.48 |
-120.02 |
0.025055 |
| 208964_s_at |
fatty acid desaturase 1 |
AL512760 |
-5.46 |
-3305.87 |
0.025757 |
| 213693_s_at |
gb:AI610869/DB_XREF=gi:4620036/DB_XREF=tp21e08.x1/CLONE= |
AI610869 |
-5.43 |
-1427.55 |
0.023253 |
| 237507_at |
keratin 6 irs3 |
AI333069 |
-5.43 |
-271.6 |
0.008082 |
| 204389_at |
monoamine oxidase A |
NM_000240 |
-5.4 |
-180.28 |
0.0359 |
| 214598_at |
claudin 8 |
AL049977 |
-5.27 |
-370.2 |
0.01827 |
| 201963_at |
acyl-CoA synthetase long-chain family member 1 |
NM_021122 |
-5.19 |
-4459.79 |
0.010049 |
| 218434_s_at |
acetoacetyl-CoA synthetase |
NM_023928 |
-5.17 |
-1842.1 |
0.004574 |
| 221552_at |
abhydrolase domain containing 6 |
BC001698 |
-5.06 |
-402.38 |
0.024809 |
|
Top 50 transcripts – based on fold difference are shown (complete list is supplied as supplementary material). | |||||
O'Driscoll et al. Molecular Cancer 2006 5:74 doi:10.1186/1476-4598-5-74 |
|||||