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Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

Guoping Sui1 email, Shaoyu Zhou2 email, Jean Wang3 email, Marcia Canto3 email, Edward E Lee6 email, James R Eshleman1,4 email, Elizabeth A Montgomery1 email, David Sidransky2,4 email, Joseph A Califano2,4 email and Anirban Maitra1,4,5 email

Department of Pathology, Johns Hopkins University School of Medicine, Washington, DC

Department of Otolaryngology and Head and Neck Surgery, Johns Hopkins University School of Medicine, Washington, DC

Department of Medicine, Johns Hopkins University School of Medicine, Washington, DC

Department of Oncology, Johns Hopkins University School of Medicine, Washington, DC

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Washington, DC

Department of Pathology, Howard University School of Medicine, Washington, DC

author email corresponding author email

Molecular Cancer 2006, 5:73doi:10.1186/1476-4598-5-73

Published: 13 December 2006

Additional files

Additional file 1:

MtDNA sequence alterations across 14 preneoplastic lesions of the gastrointestinal tract. The table enumerates the mitochondrial DNA sequence alterations detected in the individual preneoplastic lesions, and their effect on the translated protein, if any.

Format: DOC Size: 298KB Download file

This file can be viewed with: Microsoft Word Viewer


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