Table 1

Proteins from our proteomic analysis which were significantly different in ccRCC as compared to normal kidney tissue.

Symbol
Protein Name
SwissProt ID
Entrez Gene ID
Ratio RCC: normal kidney
Minimum Paired t-test

SUCLG1
succinate-CoA ligase, GDP-forming, alpha subunit
P53597
8802
0.2
0.0000
HSPCB
heat shock 90kDa protein 1, beta
P08238
3326
0.4
0.0001
ALDOB
aldolase B, fructose-bisphosphate
P05062
229
0.1
0.0001
PRDX1
peroxiredoxin 1
Q06830
5052
0.3
0.0002
ECHS1
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
P30084
1892
0.3
0.0002
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
P50440
2628
0.3
0.0003
ASS
argininosuccinate synthetase
P00966
445
0.3
0.0008
ATP5H
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d
O75947
10476
0.4
0.0010
HSPD1
heat shock 60kDa protein 1 (chaperonin)
P10809
3329
0.4
0.0019
ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
P30049
513
0.3
0.0029
PCK2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Q16822
5106
0.3
0.0033
CALB1
calbindin 1, 28kDa
P05937
793
0.3
0.0035
BHMT
betaine-homocysteine methyltransferase
Q93088
635
0.5
0.0041
ACY1
aminoacylase 1
Q03154
95
0.4
0.0043
AKR1A1
aldo-keto reductase family 1, member A1 (aldehyde reductase 2ALR)
P14550
10327
0.4
0.0054
AGMAT
agmatine ureohydrolase (agmatinase)
Q9BSE5
79814
0.5
0.0064
ACAT1
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
P24752
38
0.4
0.0078
GSTO2
glutathione-S-transferase, alpha-class, omega 2 subunit
P08263
119391
0.4
0.0101
PKM2
pyruvate kinase, muscle
P14618
5315
14.7
0.0170
ANXA4
annexin A4
Q6P452
307
2.7
0.0225
ANXA5
Annexin V
P08758
308
2.3
0.0245
HSPB1
heat shock 27kDa protein 1
P04792
3315
2.4
0.0256
FABP7
fatty acid binding protein 7, brain
O15540
2173
6.3
0.0262
TBB2
tubulin, beta polypeptide
P07437
7280
19.5
0.0264
ENO2
enolase 2, (gamma, neuronal)
P09104
2026
32.8
0.0364
LDHA
lactate dehydrogenase A
P00338
3939
3.8
0.0383
CLIC1
chloride intracellular channel 1
O00299
1192
2.8
0.0414
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
P04406
2597
2.1
0.0450
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Q9UL46
5721
2.2
0.0460
CSTB
cystatin B (stefin B)
P04080
1476
4.0
0.0464
HINT1
histidine triad nucleotide binding protein 1 (PKCi substrate analog)
P49773
3094
2.4
0.0482

Perroud et al. Molecular Cancer 2006 5:64   doi:10.1186/1476-4598-5-64