Molecular Cancer

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Epigenetic aberrations and cancer

Miryam Ducasse1 and Mark A Brown2

Author Affiliations

1 Institute for Biomedical Research Georg-Speyer-Haus, 60596 Frankfurt, Germany

2 Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, The University of Texas at Austin, 1 University Station A5000, Austin TX 78712, USA

Molecular Cancer 2006, 5:60 doi:10.1186/1476-4598-5-60

Published: 8 November 2006

Abstract

The correlation between epigenetic aberrations and disease underscores the importance of epigenetic mechanisms. Here, we review recent findings regarding chromatin modifications and their relevance to cancer.