|
Comparison of results obtained from this study with those based on Gene Ontology Processes by Sandberg et al. [7] |
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| KEGG Pathway |
Related GO category |
Direction of regulation in cell lines with respect to tumors |
|
| This study |
Gene Ontology Study [7] |
||
|
|
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| ATP synthesis |
ATP synthesis coupled proton transport (GO:0015986) |
↑ |
↑ |
| Cell cycle |
Cell cycle (GO:0007049) |
↑ |
↑ |
| One carbon pool by folate |
Nucleotide biosynthesis (GO:0009165) |
↑ |
↑ |
| Oxidative phosphorylation |
Oxidative phosphorylation (GO:0006119) |
↑ |
↑ |
| Proteasome |
Ubiquitin-dependent protein catabolism (GO:0006511); Modification-dependent protein catabolism (GO:0019941) |
↑ |
↑ |
| Purine metabolism |
Purine nucleotide metabolism (GO:0006163) |
↑ |
↑ |
| Pyrimidine metabolism |
Nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0006139) |
↑ |
↑ |
| Ribosome |
Protein biosynthesis (GO:0006412) |
↑ |
↑ |
| RNA polymerase |
Nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0006139) |
↑ |
↑ |
| Cell adhesion molecules (CAMs) |
Cell adhesion (GO:0007155) |
↓ |
↓ |
| Cell communication |
Cell adhesion (GO:0007155) |
↓ |
↓ |
| Complement and coagulation cascade |
Complement activation (GO:0006956) |
↓ |
N/A |
| ECM-receptor interaction |
Cell adhesion (GO:0007155) |
↓ |
↓ |
| Focal Adhesion |
Cell adhesion (GO:0007155) |
↓ |
↓ |
| Phenylalanine metabolism |
Phenol metabolism (GO:0018958) |
↓ |
N/A |
|
The symbol [↑] indicates upregulation in cell lines with respect to tumors and [↓] indicates downregulation in cell lines with respect to tumors (CL - T). | |||
Ertel et al. Molecular Cancer 2006 5:55 doi:10.1186/1476-4598-5-55 |
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