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SAM genes that were upregulated in cell lines compared to tumors in all the 6 tissues considered in the study (CL - T). |
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| Gene Symbol |
Gene Name |
Kegg Pathway(s) |
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| ATP5B |
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide |
Oxidative phosphorylation, ATP synthesis |
| ATP5G3 |
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) |
ATP synthesis, Oxidative phosphorylation |
| C1QBP |
complement component 1, q subcomponent binding protein |
(Immune Response) |
| CBX3 |
chromobox homolog 3 (HP1 gamma homolog, Drosophila) |
N/A |
| CCNB1 |
cyclin B1 |
Cell cycle |
| CCT5 |
chaperonin containing TCP1, subunit 5 (epsilon) |
N/A |
| CDC20 |
CDC20 cell division cycle 20 homolog (S. cerevisiae) |
Ubiquitin mediated proteolysis, Cell cycle |
| CDKN3 |
cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) |
N/A |
| CHAF1A |
chromatin assembly factor 1, subunit A (p150) |
N/A |
| CKAP1 |
cytoskeleton associated protein 1 |
N/A |
| CKS1B |
CDC28 protein kinase regulatory subunit 1B |
N/A |
| CKS2 |
CDC28 protein kinase regulatory subunit 2 |
N/A |
| COX8A |
cytochrome c oxidase subunit 8A (ubiquitous) |
Oxidative phosphorylation |
| CYC1 |
cytochrome c-1 |
Oxidative phosphorylation |
| DNMT1 |
DNA (cytosine-5-)-methyltransferase 1 |
Methionine metabolism |
| DYNLL1 |
dynein, light chain, LC8-type 1 |
N/A |
| EBNA1BP2 |
EBNA1 binding protein 2 |
N/A |
| HMGB2 |
high-mobility group box 2 |
N/A |
| KIAA0101 |
KIAA0101 |
N/A |
| KIF2C |
kinesin family member 2C |
N/A |
| LMNB2 |
lamin B2 |
Cell communication |
| MCM3 |
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) |
Cell cycle |
| MCM4 |
MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) |
Cell cycle |
| MCM7 |
MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) |
Cell cycle |
| MRPL12 |
mitochondrial ribosomal protein L12 |
N/A |
| NDUFS8 |
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) |
Oxidative phosphorylation |
| PAICS |
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
Purine metabolism |
| PCNA |
proliferating cell nuclear antigen |
Cell cycle |
| POLR2G |
polymerase (RNA) II (DNA directed) polypeptide G |
Purine metabolism, RNA polymerase, Pyrimidine metabolism |
| PRMT1 |
protein arginine methyltransferase 1 |
Selenoamino acid metabolism, Nitrobenzene degradation, Aminophosphonate metabolism, Tryptophan metabolism, Histidine metabolism, Androgen and estrogen metabolism, Tyrosine metabolism |
| PSMA1 |
proteasome (prosome, macropain) subunit, alpha type, 1 |
Proteasome |
| PSMB2 |
proteasome (prosome, macropain) subunit, beta type, 2 |
Proteasome |
| PSMB5 |
proteasome (prosome, macropain) subunit, beta type, 5 |
Proteasome |
| PSMB6 |
proteasome (prosome, macropain) subunit, beta type, 6 |
Proteasome |
| PSMD14 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 |
Proteasome |
| RANBP1 |
RAN binding protein 1 |
N/A |
| SFRS9 |
splicing factor, arginine/serine-rich 9 |
N/A |
| SNRPA |
small nuclear ribonucleoprotein polypeptide A |
N/A |
| SNRPB |
small nuclear ribonucleoprotein polypeptides B and B1 |
N/A |
| SNRPC |
small nuclear ribonucleoprotein polypeptide C |
N/A |
| SNRPD2 |
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa |
N/A |
| SNRPD3 |
small nuclear ribonucleoprotein D3 polypeptide 18kDa |
N/A |
| SNRPE |
small nuclear ribonucleoprotein polypeptide E |
N/A |
| SNRPF |
small nuclear ribonucleoprotein polypeptide F |
N/A |
| SNRPG |
small nuclear ribonucleoprotein polypeptide G |
N/A |
| TCEB1 |
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
Ubiquitin mediated proteolysis |
| TUBG1 |
tubulin, gamma 1 |
N/A |
| TXNRD1 |
thioredoxin reductase 1 |
Pyrimidine metabolism |
| TYMS |
thymidylate synthetase |
Pyrimidine metabolism, One carbon pool by folate |
| UBE2C |
ubiquitin-conjugating enzyme E2C |
Ubiquitin mediated proteolysis |
| UBE2S |
ubiquitin-conjugating enzyme E2S |
N/A |
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SAM genes shown in italic also belonged to cell lines and normal tissue comparison. There were no downregulated genes common to all tissue types in cell line-tumor (CL - T) comparisons. | ||
Ertel et al. Molecular Cancer 2006 5:55 doi:10.1186/1476-4598-5-55 |
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