Figure 6.

Integrin Beta 3 and CD31 are highly expressed in the SCCVII tumor angiogenic vessels detected by RT-PCR from laser capture microdissected endothelial cells and confirmed by immunohistochemical staining of Integrin Beta-3. Integrin immunohistochemistry on paraffin embedded 7 μm sections were stained with mouse monoclonal antibodies from BD-Pharmingen, USA at a dilution of 1:200. Positive CD31 and Beta 3 showed dark brown and intense orange-brown staining, respectively. Each tumor section was counterstained with hemotoxylin.