Down-regulation of mRNA expression in human chromosomal region 4p15.31-15.2 (patient counts with coordinate down-regulation). Grayscale cross-comparison plot of down-regulation patterns across patients (analogous to Figures 8, 11, 14). View this plot in conjunction with Figures 21 and 22. Note, that many more patients show down-regulation as indicated by dark spots in this plot than up-regulation as indicated by dark spots in Figure 22. This region has been reported in other studies to be frequently deleted in colon cancer (see Table 4). Note the expression down-regulation of SLIT2, GPR125 and PCDH7.
Staub et al. Molecular Cancer 2006 5:37 doi:10.1186/1476-4598-5-37