Table 5

Genes significantly decreased in tumors.

GeneBank Accession
Gene Description
Symbol
Normal Mean
Tumor Mean
Fold Change
P value


Cell Growth/Division





D17291
regenerating protein I beta
REG1B
6286
13
-499.46
0.000095
X67318
carboxypeptidase A1
CPA1
3928
121
-32.57
0.003205
AI763065
regenerating islet-derived 1 alpha
REG1A
5641
334
-16.88
0.000001
D29990
solute carrier family 7, member 2
SLC7A2
2988
445
-6.72
0.002204
AB017430
kinesin-like 4
KIFF22
1223
316
-3.87
0.000177
Z25884
chloride channel 1
CLCN1
2511
655
-3.84
0.00013
X81438
amphiphysin
AMPH
2686
752
-3.57
0.000002
L03785
myosin, light polypeptide 5
MYL5
207
59
-3.51
0.000233
W28062
guanine nucleotide-exch. Prot. 2
ARFGEF2
66
19
-3.46
0.003602
X52486
uracil-DNA glycosylase 2
UNG2
2555
756
-3.38
0.000514
M81933
cell division cycle 25A
CDC25A
312
96
-3.25
0.000005
M69136
chymase 1
CMA1
360
115
-3.13
0.004413
U90543
butyrophilin
BTN2A1
685
226
-3.04
0.000023
X69086
utrophin
UTRN
1325
457
-2.90
0.000011
AF039241
histone deacetylase 5
HDAC5
1124
393
-2.86
0.000319
U49392
allograft inflammatory factor 1
AIF1
165
58
-2.82
0.000105
U81992
pleiomorphic adenoma gene-like 1
PLAGL1
330
118
-2.80
0.004717
L26336
heat shock 70kD protein 2
HSPA2
90
32
-2.79
0.000689
F27891
cytochrome c oxidase subunit VIa
COX6A2
872
313
-2.79
0.000342
D87673
heat shock transcription factor 4
HSF4
1964
721
-2.73
0.000453
X97795
RAD54-like
RAD54L
392
144
-2.72
0.001345
X92689
UDP-N-acetyl-alpha-D-galactosamine
GALNT3
80
32
-2.50
0.000243
Y08683
carnitine palmitoyltransferase I
CPT1B
1038
420
-2.47
0.000573
U40622
X-ray repair complementing defective repair 4
XRCC4
177
72
-2.45
0.000678
U64315
excision repair, complementation group 4
ERCC4
2122
868
-2.44
0.000045
AB020337
beta 1,3-galactosyltransferase
B3GALT5
1489
635
-2.34
0.002613
U40152
origin recognition complex
ORC1L
3671
1702
-2.16
0.001425
M10943
metallothionein 1F
MT1F
5691
2653
-2.14
0.001707
X79882
major vault protein
MVP
758
376
-2.02
0.001719
AF035960
transglutaminase 5
TGM5
3097
1542
-2.01
0.002951








Cell Death/Apoptosis





S81914
immediate early response 3
IER3
2209
480
-4.60
0.000307
D80007
programmed cell death 11
PDCD11
457
129
-3.55
0.002358
AF013956
chromobox homolog 4
CBX4
1599
492
-3.25
0.00034
U33284
protein tyrosine kinase 2 beta
PTK2B
693
237
-2.93
0.000763
U90919
likely partner of ARF1
APA1
2687
1021
-2.63
0.000015
X57110
Cas-Br-M retroviral transforming
CBL
1889
784
-2.41
0.000033
AL050161
pro-oncosis receptor
PORIMIN
1178
497
-2.37
0.00031
U40380
presenilin 1
PSEN1
1301
569
-2.29
0.00012
D83699
harakiri, BCL2 interacting protein
HRK
768
338
-2.27
0.001321
U07563
v-abl viral oncogene homolog 1
ABL1
1415
631
-2.24
0.000248
M95712
v-raf oncogene homolog B1
BRAF
338
157
-2.16
0.004207
M16441
lymphotoxin alpha
LTA
2106
985
-2.14
0.000239
AF035444
pleckstrin homology-like domain, family A, member 2
PHLDA2
334
166
-2.01
0.001759

Dilley et al. Molecular Cancer 2005 4:9   doi:10.1186/1476-4598-4-9