|
Genes in amplicons of chromosome 2, 8 and 20. |
|||||||
| Genes in amplicon of Chromosome 20 |
|||||||
|
|
|||||||
| Unigene ID |
Gene symbol |
Position (Kb)* |
Genomic values |
Expression values |
Genetic data** |
Expression data** |
|
|
|
|||||||
| 20p13 |
Hs.356727 |
FKBP1A |
- |
1,918 |
4,022 |
0,940 |
2,008 |
| Hs.155140 |
CSNK2A1 |
451 |
n.d. |
1,678 |
n.d |
0,747 |
|
| Hs.156114 |
PTPNS1 |
1,505 |
1,635 |
0,868 |
0,709 |
-0,205 |
|
| Hs.26045 |
PTPRA |
2,832 |
1,279 |
0,251 |
0,355 |
-1,997 |
|
| Hs.89648 |
AVP |
3,051 |
n.d. |
1,274 |
n.d |
0,349 |
|
| Hs.85004 |
CENPB |
3,753 |
1,703 |
1,169 |
0,768 |
0,226 |
|
| Hs.153752 |
CDC25B |
3,765 |
2,122 |
1,761 |
1,079 |
0,811 |
|
| Hs.80905 |
RASSF2 |
4,748 |
1,25 |
0,981 |
0,322 |
-0,028 |
|
| Hs.78996 |
PCNA |
5,083 |
1,694 |
8,187 |
0,760 |
3,033 |
|
| Hs.2281 |
CHGB |
5,880 |
n.d. |
0,855 |
n.d |
-0,226 |
|
| Hs.73853 |
BMP2 |
6,737 |
2,694 |
n.d. |
1,430 |
n.d |
|
| Hs.91143 |
JAG1 |
10,606 |
1,89 |
0,953 |
0,918 |
-0,069 |
|
| Hs.44296 |
FLJ22324 |
13,761 |
1,543 |
2,292 |
0,626 |
1,197 |
|
| Hs.82306 |
ADF |
17,538 |
1,43 |
0,475 |
0,516 |
-1,075 |
|
| Hs.268281 |
CRN |
20,003 |
1,458 |
1,034 |
0,544 |
0,048 |
|
| Hs.2030 |
THBD |
23,016 |
1,655 |
0,572 |
0,727 |
-0,806 |
|
| Hs.1872 |
PCK1 |
24,899 |
1,482 |
0,824 |
0,568 |
-0,279 |
|
| Hs.274264 |
VSX1 |
25,044 |
1,67 |
1,682 |
0,740 |
0,750 |
|
| Hs.75424 |
ID1 |
29,981 |
3,825 |
1,640 |
1,935 |
0,714 |
|
| 20q11 |
Hs.305890 |
BCL2L1 |
30,040 |
6,941 |
11,508 |
2,795 |
3,525 |
|
|
|||||||
| Genes in amplicon of chromosome 2 |
|||||||
|
|
|||||||
| Unigene ID |
Gene symbol |
Position (Kb)* |
Genomic values |
Expression values |
Genomic data** |
Expression data** |
|
|
|
|||||||
| 2q34 |
Hs.54089 |
BARD1 |
218,722 |
0,734 |
1,646 |
-0,446 |
0,719 |
| Hs.84981 |
XRCC5 |
220,094 |
1,823 |
2,815 |
0,856 |
1,341 |
|
| Hs.162 |
IGFBP2 |
220,592 |
2,563 |
4,544 |
1,358 |
2,184 |
|
| Hs.107169 |
IGFBP5 |
220,635 |
2,034 |
0,820 |
1,024 |
-0,285 |
|
| Hs.38125 |
IFI75 |
224,000 |
1,342 |
1,664 |
0,413 |
0,647 |
|
| Hs.309943 |
SP140 |
224,057 |
1,45 |
0,646 |
0,536 |
-0,631 |
|
| Hs.83583 |
ARPC2 |
226,590 |
1,058 |
0,648 |
0,081 |
-0,626 |
|
| Hs.166068 |
VIL1 |
226,796 |
1,025 |
1,463 |
0,036 |
0,549 |
|
| Hs.82568 |
CYP27A1 |
227,154 |
1,676 |
0,764 |
0,745 |
-0,388 |
|
| Hs.88049 |
PRKAG3 |
227,195 |
2,091 |
0,436 |
1,064 |
-1,196 |
|
| Hs.153003 |
STK16 |
227,618 |
1,657 |
1,272 |
0,729 |
0,347 |
|
| Hs.75318 |
TUBA1 |
227,622 |
1,631 |
5,622 |
0,706 |
2,491 |
|
| Hs.77768 |
DNAJB2 |
227,652 |
1,82 |
0,841 |
0,864 |
-0,250 |
|
| Hs.89655 |
PTPRN |
227,662 |
1,659 |
1,447 |
0,730 |
0,533 |
|
| Hs.48291 |
PDE6D |
227,901 |
1,122 |
0,520 |
0,166 |
-0,943 |
|
| Hs.1734 |
INHA |
228,352 |
1,187 |
0,849 |
0,247 |
-0,237 |
|
| Hs.198 |
PAX3 |
230,984 |
1,677 |
1,504 |
0,746 |
0,589 |
|
| Hs.78946 |
CUL3 |
233,252 |
1,18 |
0,997 |
0,239 |
-0,004 |
|
| Hs.75498 |
SCYA20 |
236,823 |
1,347 |
0,293 |
0,430 |
-1,769 |
|
| Hs.91400 |
HDAC4 |
243,313 |
1,26 |
0,543 |
0,333 |
-0,881 |
|
| Hs.36587 |
PPP1R7 |
244,757 |
0,907 |
1,859 |
-0,141 |
0,895 |
|
| 2q37 |
Hs.5345 |
RNPEPL1 |
245,348 |
1,488 |
0,949 |
0,573 |
-0,076 |
| 2q35 |
Hs.82793 |
PSMB3 |
- |
1,794 |
3,874 |
0,843 |
1,954 |
|
|
|||||||
| Genes in amplicon of chromosome 8 |
|||||||
|
|
|||||||
| Unigene ID |
Gene symbol |
Position (Kb)* |
Genomic values |
Expression values |
Genomic data** |
Expression data** |
|
|
|
|||||||
| 8q23 |
Hs.114218 |
FZD6 |
105,144 |
0,980 |
0,621 |
-0,030 |
-0,717 |
| Hs.86905 |
ATP6C |
105,407 |
1,067 |
0,918 |
0,094 |
-0,123 |
|
| Hs.82173 |
TIEG |
105,820 |
1,277 |
0,842 |
0,353 |
-0,248 |
|
| Hs.94262 |
p53R2 |
106,237 |
1,324 |
0,564 |
0,369 |
-0,831 |
|
| Hs.2463 |
ANGPT1 |
109,654 |
1,745 |
n.d |
0,803 |
n.d. |
|
| Hs.106673 |
EIF3S6 |
111,104 |
1.170 |
0.402 |
0.227 |
-1.314 |
|
| Hs.58189 |
EIF3S3 |
119,873 |
1,097 |
0,566 |
0,130 |
-0,885 |
|
| Hs.184161 |
EXT1 |
121,031 |
1,260 |
3,592 |
0,333 |
1,845 |
|
| Hs.174185 |
ENPP2 |
122,788 |
1,223 |
0,891 |
0,290 |
-0,167 |
|
| Hs.12940 |
ZHX1 |
127,568 |
1,212 |
1,309 |
0,277 |
0,389 |
|
| Hs.61661 |
- |
127,822 |
1,101 |
1,318 |
0,139 |
0,399 |
|
| Hs.181107 |
ANXA13 |
127,989 |
1,333 |
0,655 |
0,415 |
-0,611 |
|
| Hs.344478 |
KIAA0196 |
129,211 |
1,302 |
n.d |
0,381 |
n.d |
|
| Hs.79070 |
MYC |
132,293 |
1,883 |
1,597 |
0,853 |
0,630 |
|
| Hs.305916 |
TG |
136,747 |
1,441 |
1,711 |
0,527 |
0,775 |
|
| Hs.75789 |
NDRG1 |
137,117 |
1,617 |
1,140 |
0,693 |
0,190 |
|
| Hs.157240 |
MGC4737 |
143,611 |
1,722 |
0,828 |
0,784 |
-0,273 |
|
| Hs.740 |
PTK3 |
144,545 |
1,896 |
0,939 |
0,914 |
-0,487 |
|
| Hs.77667 |
LY6E |
146,427 |
1,595 |
2,410 |
0,674 |
1,269 |
|
| Hs.301118 |
CYP11B1 |
146,498 |
1,619 |
1,227 |
0,695 |
0,295 |
|
| Hs.348605 |
- |
146,918 |
1,309 |
0,826 |
0,388 |
-0,276 |
|
| Hs.264428 |
TSTA3 |
147,413 |
1,365 |
0,693 |
0,449 |
-0,530 |
|
| Hs.223241 |
EEF1D |
147,485 |
1,554 |
3,142 |
0,636 |
1,651 |
|
| Hs.323834 |
NFKBIL2 |
147,600 |
1,375 |
4,436 |
0,459 |
2,149 |
|
| Hs.339697 |
LOC51160 |
147,616 |
1,418 |
1,546 |
0,504 |
0,629 |
|
| Hs.31442 |
RECQL4 |
147,653 |
1,458 |
3,419 |
0,544 |
1,774 |
|
| Hs.12271 |
- |
147,813 |
1,640 |
2,034 |
0,714 |
1,024 |
|
| Hs.92679 |
- |
147,876 |
1,178 |
1,510 |
0,236 |
0,595 |
|
| 8q24 |
Hs.331601 |
- |
147,927 |
2,138 |
1,077 |
1,096 |
0,107 |
|
Areas of genomic gain presenting the highest values are shown in bold. Note that in 20p amplicon, the entire region is gained, but only the highest values are indicated. Underlined are gained and overexpressed genes. *Map location according to the EnsMBL database (with exception of FKBP1A and PSMB3 genes that are FISH mapped); **Log2 values; n.d. No data. | |||||||
Meléndez et al. Molecular Cancer 2005 4:5 doi:10.1186/1476-4598-4-5 |
|||||||