Table 1

Genes highly gained and overexpressed in huT78 cell line.

Unigene ID
Gene Symbol
G
E
Log2(G)
Log2(E)
Cytogenetic Location
Gene

Hs.76884
ID3
1,857
2,343
0,893
1,228
1p36.13-p36.12
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Hs.84981
XRCC5
2,04
4,044
1,029
2,016
2q35
X-ray repair complementing defective repair in Chinese hamster cells 5
Hs.162
IGFBP2
2,563
4,544
1,358
2,184
2q33-34
insulin-like growth factor binding protein 2
Hs.82793
PSMB3
1,794
3,874
0,843
1,954
2q35
proteasome subunit, beta type, 3
Hs.174007
VHL
3,119
2,044
1,641
1,031
3p26-p25
von Hippel-Lindau syndrome
Hs.55173
CELSR3
1,862
2,647
0,897
1,404
3p24.1-p21.2
cadherin, EGF LAG seven-pass G-type receptor 3
Hs.180145
HSPC030
1,777
2,947
0,829
1,559
3
HSPC030 protein
Hs.350266
ARGBP2
1,823
2,028
0,866
1,020
4q35.1
Arg/Abl-interacting protein ArgBP2
Hs.179565
MCM3
1,791
4,378
0,841
2,130
6p12
MCM3 minichromosome maintenance deficient 3
Hs.278589
GTF2I
1,886
2,379
0,915
1,251
7q11.23
general transcription factor II, i
Hs.167246
POR
2,007
2,609
1,005
1,384
7q11.2
P450 (cytochrome) oxidoreductase
Hs.61762
HIG2
1,885
3,152
0,915
1,656
7q32.2
hypoxia-inducible protein 2
Hs.274424
SAS
1,743
4,944
0,802
2,306
9p24.1-p23
N-acetylneuraminic acid phosphate synthase; sialic acid synthase
Hs.184793
DKFZP434F195
1,78
2,125
0,832
1,087
9
DKFZP434F195 protein
Hs.18910
POV1
1,78
3,702
0,832
1,888
11p11.2-p11.1
prostate cancer overexpressed gene 1
Hs.91877
THRSP
6,491
3,095
2,698
1,630
11q13.5
thyroid hormone responsive
Hs.180628
DNM1L
1,758
2,715
0,814
1,441
12p12.3
dynamin 1-like
Hs.76294
CD63
1,747
6,165
0,805
2,624
12q12-q13
CD63 antigen (melanoma 1 antigen)
Hs.247888
-
2,284
3,201
1,192
1,679
16

Hs.12303
SUPT6H
1,742
2,819
0,801
1,495
17q11.2
suppressor of Ty 6 homolog (S. cerevisiae)
Hs.296281
ILF1
1,754
3,146
0,811
1,653
17q25
interleukin enhancer binding factor 1
Hs.75716
SERPINB2
2,358
3,767
1,238
1,913
18q21.3
serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
Hs.8372
UQCR
2,046
2,916
1,033
1,544
19p13.3
ubiquinol-cytochrome c reductase subunit
Hs.661
NDUFB7
1,845
2,416
0,884
1,272
19p13.12-p13.11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
Hs.36992
-
4,848
3,213
2,277
1,684
19

Hs.250615
CYP2A7
1,778
3,718
0,830
1,895
19q13.2
cytochrome P450, subfamily IIA, polypeptide 7
Hs.356727
FKBP1A
1,918
4,022
0,940
2,008
20p13
FK506 binding protein 1A
Hs.305890
BCL2L1
6,941
11,508
2,795
3,525
20q11.21
BCL2-like 1, Bcl-X
Hs.273385
GNAS
1,764
2,059
0,819
1,042
20q13.2-q13.3
GNAS complex locus
Hs.284380
GGT1
1,784
2,762
0,835
1,466
22q11.23
gamma-glutamyltransferase 1

Relation of 30 genes presenting genomic values ≥ 1.7 [log2(G) ≥ 0,8] and expression values ≥ 2 [log2(E) ≥ 1]; it represents gains above 4-fold and overexpression above 2-fold. In bold, genes located in amplicons. G, Genomic values; E, Expression values.

Meléndez et al. Molecular Cancer 2005 4:5   doi:10.1186/1476-4598-4-5