|
Up-regulated genes in rats fed with SPI diet* |
|||
| Category and Gene Name |
Probe Set GB Accession No. |
Fold Change |
P value |
|
|
|||
| Cell adhesion |
|||
| Collagen alpha1 type I |
Z78279 |
2.49 |
0 |
| Secreted phosphoprotein 1 |
M14656 |
111.39 |
0.006 |
| Matrix metalloproteinase 13 |
M60616 |
24.34 |
0.002 |
| Regenerating islet |
M62930 |
193.08 |
0.011 |
| Defense/immunity protein |
|||
| Ig gamma-2a chain |
L22654 |
115.17 |
0.001 |
| Ig gamma heavy chain |
M28670 |
3.22 |
0 |
| Ig germline kappa-chain C-region |
M18528 |
2.48 |
0.038 |
| Ig light-chain |
U39609 |
2.63 |
0.021 |
| Fc-gamma |
M32062 |
4.72 |
0.017 |
| Detoxification |
|||
| Glutathione S-transferase 1 |
J03752 |
2.86 |
0 |
| Glutathione-S-transferase,alpha type2 |
K00136 |
2.56 |
0.009 |
| UDP glucuronosyltransferase |
D38066 |
2.83 |
0.014 |
| Metabolism |
|||
| Matrix metalloproteinase 7 |
L24374 |
3.63 |
0.02 |
| lysozyme |
rc_AA892775 |
2.77 |
0 |
| Matrix metalloproteinase 12 |
X98517 |
11.8 |
0.013 |
| Mitochondrial carbamyl phosphate synthetase I |
M12335 |
59.25 |
0.001 |
| Aldolase B, exon 9 |
X02291 |
8.7 |
0.01 |
| Aldolase B, exon 2 |
X02284 |
2.71 |
0.001 |
| Signal transduction |
|||
| MHC class II antigen RT1.B-1 beta-chain |
X56596 |
2.55 |
0.001 |
| CD3 gamma-chain |
S79711 |
4.51 |
0.001 |
| Ligand binding/carrier |
|||
| Intracellular calcium-binding protein |
L18948 |
28.29 |
0.014 |
| Retinol binding protein II |
M13949 |
5.11 |
0.001 |
| Apolipoprotein B |
M27440 |
6.47 |
0.024 |
| Apolipoprotein A-I |
J02597 |
2.49 |
0.004 |
| Iron ion transporter |
AF008439 |
18.78 |
0.008 |
| Stress response/apoptosis |
|||
| Heme oxygenase |
J02722 |
9.66 |
0.002 |
| JE product |
X17053 |
3.52 |
0.001 |
| Pancreatitis-associated protein |
M98049 |
68.39 |
0.004 |
| Pancreatitis associated protein III |
L20869 |
15.35 |
0 |
| Reg protein |
E01983 |
30.25 |
0.001 |
| Others |
|||
| Histamine N-tele-methyltransferase |
S82579 |
6.17 |
0.04 |
|
*Changes in gene expression were determined by t-test (DMT), comparative analysis (MAS 5.0), and SAM (Stanford). Gene expression profiles from CAS animals were used as control. P value and fold-change are based on the DMT analysis; whereas final listed genes met all of the analytical criteria as described in the Methods. | |||
Xiao et al. Molecular Cancer 2005 4:1 doi:10.1186/1476-4598-4-1 |
|||