|
Endothelial cell genes (ECG) detected by SSHDD. BLAST searches revealed similarity to the accession # provided on the right most column. Genbank accession number in bold letter denotes complete cDNA sequence deposited by the authors. |
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| Class of genes |
Gen Bank Accession Number |
Reference |
|
|
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| Known Genes associated with the activation of endothelial cells |
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| Matrix metalloproteinases-1 (MMP-1) |
X54925 |
3,25,26 |
| Matrix metalloproteinases-2 (MMP2) |
NM_ 004530 |
3,25,26 |
| Stromelysin (MMP-3) |
X05232 |
2,3,25 |
| Type IV collagenase (MMP9) |
J05070 |
2,3,26 |
| Myeloblastin |
M75154 |
25,26 |
| Cathepsin B |
M14221 |
28 |
| Calpastatin |
E02261 |
29 |
| Urokinase plasminogen activator surface receptor (uPAR) |
X51675 |
2,30 |
| Vascular endothelial growth factor receptor (VEGFR1/FLT-1) |
AF063657 |
4,5 |
| Vascular endothelial growth factor receptor-2(VEGFR-2/KDR) |
X61656 |
4,5,6 |
| Vascular cell adhesion molecule-1 (VCAM-1) |
X53051 |
2,3 |
| α2 integrin subunit |
X17033 |
2,20 |
| VE-cadherin |
X79981 |
2,3,21 |
| Prostaglandin endoperoxidase (Cox) |
E03346 |
2,32 |
| Metabolic and miscellaneous genes |
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| Ketohexokinase |
P50053 |
- |
| Adenosine deaminase |
X02994 |
- |
| Spermidine synthase |
M64231 |
- |
| Adenylyl cyclase |
X74210 |
33 |
| Platelet factor 4 (PF4) |
M25897 |
34 |
| Stanniocalcin |
U25997 |
35,36 |
| Candidate genes associated with the activation of endothelial cells |
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| Clone 7D Kinesin-heavy chain (KHC) |
X65873 |
37 |
| Clone 17E Epiregulin (Epireg) |
NM_001432 |
38 |
| Clone 22G Similar to transcription factor BTF3 |
XM_038290 |
40 |
| Clone 33A Phosphatidic acid phosphatase-2b (PAP2b/VCIP) |
AB000889/AF480883 |
40,41 |
| Clone 37F Synaptojanin-2 (similar to KIAA0348 protein) |
AB002346 |
42,43 |
| Clone 48A Similar to GPCR kinase-interactor-2 (GIT-2) |
NM_014776 |
44 |
| Clone 54C Smg GDS-associated protein (SMAP) |
AI401257/U59919 |
45 |
| Clone 77D Angiopoietin related protein (AngRP) |
AF169312 |
46 |
| Clone 94H Similar to Ribosomal protein L19 (RibL19) |
AB019566/BC013016 |
47,48 |
| Clone 263F Eukaryotic translation EF-1 alpha l(EF-lal) |
BC028674 |
49 |
| Clone 309C Stabilin-1 |
NM_015136 |
50 |
Wary et al. Molecular Cancer 2003 2:25 doi:10.1186/1476-4598-2-25 |
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