Table 1

Frequency of promoter hypermethylation in cervical carcinoma

Gene


Specimen type

No. studied

Any gene

CDH1

DAPK

RARB

HIC1

FHIT

RASSF1A

APC

CDKN2A

MGMT

BRCA1

TP73

TIMP3

GSTP1

MLH1


Controls

8

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

CC cell lines

8

8 (100)

1 (12.5)

2 (25)

6 (75)

5 (62.5)

1 (12.5)

3 (37.5)

0

1 (12.5)

2 (25)

0

2 (25)

0

1 (12.5)

1 (12.5)

Primary tumors

82

71 (86.6)

45 (54.9)

37 (45.1)

24 (29.3)

15 (18.3)

9 (11)

6 (7.3)

9 (11)

7 (8.5)

4 (4.9)

5 (6.1)

0

1 (1.2)

0

0


Figures in parenthesis indicate percentage

Narayan et al. Molecular Cancer 2003 2:24   doi:10.1186/1476-4598-2-24

Open Data