Table 1

IL-17 affects the production of inflammatory cytokines of HCC

Huh7 (pg/ml)

SMMC7721 (pg/ml)

IL-17 (50 ng/ml)

-

+

p

-

+

p

IL-6

7.0 ± 1.5

40.5 ± 19.6

< 0.001

63.3 ± 33.8

380.9 ± 198.2

0.001

IL-1β

5.3 ± 0.4

5.53 ± 0.5

0.397

6.4 ± 1.6

5.6 ± 1.0

0.261

TNF-α

22.5 ± 2.3

21.3 ± 1.2

0.206

22.8 ± 3.3

26.6 ± 6.0

0.137

TGF-β

215.7 ± 51.9

206.5 ± 47.5

0.716

140.7 ± 83.2

143.6 ± 41.5

0.931

IL-8

25.4 ± 13.1

141.3 ± 133.9

0.029

208.9 ± 144.5

521.7 ± 208.3

0.004

G-CSF

10.9 ± 1.2

11.4 ± 2.0

0.575

20.3 ± 14.9

39.3 ± 28.1

0.112

GM-CSF

6.5 ± 0.5

8.3 ± 3.8

0.212

8.40 ± 2.23

15.3 ± 9.9

0.078

VEGF

2236.4 ± 300.3

3814.5 ± 1188.6

0.043

332.0 ± 157.7

557.8 ± 162.2

0.014

MMP2

327.6 ± 12.2

492.8 ± 44.5

< 0.001

351.4 ± 14.3

558.6 ± 91.2

< 0.001

ELISA-determined cytokine levels were expressed as mean ± SD. p-values were calculated by Student's t test.

Gu et al. Molecular Cancer 2011 10:150   doi:10.1186/1476-4598-10-150